Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | FCER2 | P06734 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449428 | 0.91 | FPR2 (0.39) | CTSSFPR2CHRM4P2RX7ACHE | |
| SCHEMBL5337780 | 0.87 | MMP8 (0.41) | MMP9ADAM17MMP2MMP3MMP1 | |
| SCHEMBL5379847 | 0.79 | MMP2 (0.41) | MMP9ADAM17MMP2MMP3MMP1 | |
| SCHEMBL5450417 | 0.77 | MMP2 (0.39) | MMP9ADAM17MMP2MMP3MMP1 | |
| SCHEMBL5474229 | 0.77 | CTSS (0.37) | CTSSEPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5345342 | 0.77 | MMP2 (0.44) | MMP9ADAM17MMP2MMP3MMP1 | |
| SCHEMBL27680758 | 0.76 | SLC6A4 (0.37) | EPHX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2247550 | 0.75 | CHRM4 (0.49) | CTSSCHRM4CHRM2 | |
| SCHEMBL5378455 | 0.75 | MMP2 (0.42) | MMP9ADAM17MMP2MMP3MMP1 | |
| SCHEMBL5373840 | 0.75 | MMP2 (0.37) | MMP9ADAM17MMP2MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | Applied Research Systems ARS Holding N.V. (AN) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010751-A1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2006-02-02 | — | — | WO | disclosed |