Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15270980 | 0.78 | LMNA (0.66) | TP53TSHRLMNAMMP9MMP8 | |
| SCHEMBL9191267 | 0.77 | LMNA (0.64) | TP53TSHRLMNAMMP9MMP8 | |
| SCHEMBL6414796 | 0.77 | LMNA (0.64) | TP53TSHRLMNAMMP9MMP8 | |
| SCHEMBL9189425 | 0.77 | LMNA (0.64) | TP53TSHRLMNAMMP9MMP8 | |
| SCHEMBL14599980 | 0.77 | LMNA (0.64) | TP53TSHRLMNAMMP9MMP8 | |
| SCHEMBL9193732 | 0.77 | LMNA (0.64) | TP53TSHRLMNAMMP9MMP8 | |
| SCHEMBL9194774 | 0.77 | LMNA (0.64) | TP53TSHRLMNAMMP9MMP8 | |
| SCHEMBL19415099 | 0.75 | NR5A1 (0.67) | TP53TSHRLMNAMMP9MMP8 | |
| SCHEMBL9665074 | 0.75 | TP53 (0.78) | TP53TSHRLMNAPLA2G4BRARB | |
| SCHEMBL9474072 | 0.75 | MMP9 (0.70) | TP53TSHRLMNAMMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722934-B2 | Diphenylmethane compound | AJINOMOTO CO., INC. (JP) | 2014-05-13 | — | — | US | disclosed |
| EP-2415745-A1 | DIPHENYLMETHANE COMPOUND | Ajinomoto Co., Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20100249374-A1 | DIPHENYLMETHANE COMPOUND | AJINOMOTO CO., INC. (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249374-A1 | DIPHENYLMETHANE COMPOUND | CCKAR, DNPEP, QPCTL | TP53 1289/4885TSHR 2188/4885LMNA 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.