Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 3/20 | 0.57 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14599980 | 1.00 | LMNA (0.64) | LMNATP53TSHRPOLBPLA2G4B | |
| SCHEMBL9861070 | 0.98 | LMNA (0.62) | LMNATP53TSHRPOLBPLA2G4B | |
| SCHEMBL9000258 | 0.96 | RARB (0.65) | LMNATP53TSHRPOLBPLA2G4B | |
| SCHEMBL14599721 | 0.95 | GPR88 (0.59) | LMNATP53TSHRPOLBPLA2G4B | |
| SCHEMBL27859167 | 0.89 | TP53 (0.59) | LMNATP53TSHRPOLBPLA2G4B | |
| SCHEMBL8403335 | 0.89 | GPR88 (0.59) | LMNAGPR88RARB | |
| SCHEMBL7403967 | 0.89 | GPR88 (0.59) | LMNAGPR88RARB | |
| SCHEMBL1532485 | 0.88 | POLB (0.53) | LMNATP53TSHRPOLBMMP9 | |
| SCHEMBL9585079 | 0.87 | AKR1C3 (0.72) | LMNATP53TSHRPOLBPLA2G4B | |
| SCHEMBL9586060 | 0.87 | AKR1C3 (0.72) | LMNATP53TSHRPOLBPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801561-B1 | COMPOSITION AND METHODS FOR TRANSDERMAL DELIVERY OF ACID-LABILE DRUGS | NOVEN PHARMA (US) | 2005-04-06 | — | — | EP | claimed |
| US-20040058898-A1 | Pharmaceutical composition for alleviating the violence of a mammal comprising nortestosterone derivatives | JUNG CHANG-EUN (KR) | 2004-03-25 | — | — | US | claimed |
| EP-0801561-B1 | COMPOSITION AND METHODS FOR TRANSDERMAL DELIVERY OF ACID-LABILE DRUGS | NOVEN PHARMA (US) | 2005-04-06 | — | — | EP | disclosed |
| US-20040058898-A1 | Pharmaceutical composition for alleviating the violence of a mammal comprising nortestosterone derivatives | JUNG CHANG-EUN (KR) | 2004-03-25 | — | — | US | disclosed |
| EP-1021204-A2 | BIOADHESIVE COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF ACTIVE AGENTS | NOVEN PHARMACEUTICALS, INC. (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1999015210-A2 | BIOADHESIVE COMPOSITIONS AND METHODS FOR TOPICAL ADMINISTRATION OF ACTIVE AGENTS | NOVEN PHARMACEUTICALS, INC. (US) | 1999-04-01 | — | — | WO | disclosed |
| WO-1998053863-A2 | COMPOSITION AND METHODS FOR TRANSDERMAL DELIVERY OF ACID LABILE DRUGS | NOVEN PHARMACEUTICALS, INC. (US) | 1998-12-03 | — | — | WO | disclosed |
| US-5407681-A | Increased feed efficiency | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1995-04-18 | — | — | US | disclosed |
| US-5208032-A | INCREASING THE GROWTH OF TURKEYS USING IMPLANT OF 19-NORTESTOSTERONE | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1993-05-04 | — | — | US | disclosed |
| US-3937700-A | Novel 1,2-methylene-17α-acyloxy (or improved hydroxy)-9β, 10α-steroid compounds of the pregnane series, pharmaceutic preparations on the basis of the novel compounds and methods of producing said compounds and preparations | U.S. PHILIPS CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |