Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | AKT1 | P31749 | 3/20 | 0.49 |
| ▸ | AKT2 | P31751 | 3/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5340730 | 0.84 | ALDH1A1 (0.56) | GRIA1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL5337928 | 0.83 | AKT1 (0.52) | AKT1AKT2GRIA1KDM4ECASP1 | |
| SCHEMBL5478849 | 0.81 | AKT1 (0.55) | AKT1AKT2GRIA1LMNAKDM4E | |
| SCHEMBL5340645 | 0.80 | AKT1 (0.54) | AKT1AKT2GRIA1LMNAKDM4E | |
| SCHEMBL5341869 | 0.78 | AKT2 (0.47) | AKT1AKT2GRIA1KDM4ECASP1 | |
| SCHEMBL5348576 | 0.76 | AKT1 (0.65) | AKT1AKT2NPC1LMNARAB9A | |
| SCHEMBL5351210 | 0.76 | CNR1 (0.54) | CNR1AKT1AKT2NPC1RAB9A | |
| SCHEMBL15071102 | 0.75 | CNR1 (0.49) | CNR1AKT1AKT2KDM4EALDH1A1 | |
| SCHEMBL5342230 | 0.75 | CNR1 (0.56) | CNR1AKT1AKT2NPC1RAB9A | |
| SCHEMBL5318690 | 0.75 | CNR1 (0.58) | CNR1GRIA1ALOX15NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |