Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.65 |
| ▸ | AKT2 | P31751 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TSPO | P30536 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451404 | 0.89 | AKT1 (0.54) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5452695 | 0.89 | AKT1 (0.54) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5337928 | 0.82 | AKT1 (0.52) | AKT1AKT2TSPO | |
| SCHEMBL5340819 | 0.80 | AKT1 (0.46) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5338476 | 0.80 | GABRA2 (0.48) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5343717 | 0.80 | GABRA2 (0.48) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5335250 | 0.80 | GABRA2 (0.48) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5478849 | 0.80 | AKT1 (0.55) | AKT1AKT2LMNA | |
| SCHEMBL360182 | 0.79 | AKT1 (1.00) | AKT1AKT2 | |
| SCHEMBL5340645 | 0.79 | AKT1 (0.54) | AKT1AKT2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |