Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | PRKDC | P78527 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715769 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL22231552 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL29976495 | 0.83 | PRKDC (0.74) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL13271943 | 0.83 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL25692518 | 0.83 | PRKDC (0.74) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL1853345 | 0.82 | LMNA (0.45) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| Asaraldehyde SCHEMBL29456596 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| Asaraldehyde SCHEMBL333451 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| SCHEMBL8710876 | 0.81 | ALDH1A1 (0.55) | ALDH1A1KDM4ETSHRTDP1PRKDC | |
| Asaraldehyde SCHEMBL27489564 | 0.80 | ALDH1A1 (0.95) | ALDH1A1KDM4ETSHRTDP1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828269-B1 | BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF PI3K-ALPHA AND/OR BETA | COUNCIL SCIENT IND RES (IN) | 2018-05-16 | — | — | EP | disclosed |
| CN-104395325-B | With the LIPHAGANE compound of boric acid as the inhibitor of PI3K-α and/or β | 科学与工业研究委员会 | 2016-12-07 | — | — | CN | disclosed |
| US-9206201-B2 | Boronic acid bearing liphagane compounds as inhibitors of P13K-α and/or β | COUNSEL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-08 | — | — | US | disclosed |
| US-9206201-B2 | Boronic acid bearing liphagane compounds as inhibitors of P13K-α and/or β | COUNSEL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-08 | — | — | US | disclosed |
| CN-104395325-A | Boronic acid bearing liphagane compounds as inhibitors of pi3k-alpha and/or beta | COUNCIL SCIENT IND RES | 2015-03-04 | — | — | CN | disclosed |
| US-20150051173-A1 | BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF P13K- a AND/OR B | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-02-19 | — | — | US | disclosed |
| EP-2828269-A1 | BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF PI3K-alpha AND/OR beta | Council of Scientific & Industrial Research (IN) | 2015-01-28 | — | — | EP | disclosed |
| WO-2013140417-A1 | BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF PI3K-α AND/OR β | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-09-26 | — | — | WO | disclosed |
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7105680-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2006-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051173-A1 | BORONIC ACID BEARING LIPHAGANE COMPOUNDS AS INHIBITORS OF P13K- a AND/OR B | PIK3CA, PIK3C2A, PI4KA | ALDH1A1 3574/4885KDM4E 985/4885TSHR 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.