Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123198 | 0.86 | POLB (0.45) | KDM4EGPR3PDE10A | |
| SCHEMBL5341134 | 0.84 | LOXL2 (0.42) | KDM4EGPR3KMT2ATOP2AHDAC6 | |
| SCHEMBL19475394 | 0.79 | POLB (0.44) | KDM4EGPR3PDE10A | |
| SCHEMBL15722032 | 0.79 | PARP1 (0.59) | KDM4ETNKS2PDE4APDE4BPDE4C | |
| SCHEMBL29769683 | 0.79 | PARP1 (0.59) | KDM4ETNKS2PDE4APDE4BPDE4C | |
| SCHEMBL24415021 | 0.78 | PDE10A (0.40) | KDM4EGPR3TNKS2RAB9APDE10A | |
| SCHEMBL29977924 | 0.78 | RAB9A (0.42) | KDM4EGPR3TNKS2RAB9APDE4A | |
| SCHEMBL1424370 | 0.78 | PARP1 (0.55) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14465824 | 0.78 | RAB9A (0.42) | KDM4EGPR3TNKS2RAB9APDE4A | |
| SCHEMBL7622606 | 0.77 | KIF11 (0.41) | KDM4EKMT2ATNKS2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079086-A1 | PYRAZOLOALKYL SUBSTITUTED IMIDAZO RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-12 | — | — | WO | disclosed |