SCHEMBL533825

SCHEMBL533825

CCCCCCCCCCCCCCCCCCCCCCOc1ccc(C(=O)c2ccc(OCCCCCCCCCCCCCCCCCCCCCC)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.77
TSHR P16473 1/20 0.77
PLA2G4B P0C869 6/20 0.75
RARB P10826 3/20 0.71
PLA2G4A P47712 1/20 0.67
GAA P10253 1/20 0.65
NR5A1 Q13285 1/20 0.65
THRA P10827 2/20 0.63
THRB P10828 2/20 0.63
L3MBTL1 Q9Y468 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8769734 1.00 TP53 (0.77) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL6705357 1.00 TP53 (0.77) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL15154875 1.00 TP53 (0.77) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL1623628 1.00 TP53 (0.77) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL18302060 1.00 TP53 (0.77) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL17203727 0.98 TP53 (0.74) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL8769969 0.94 TP53 (0.68) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL6648277 0.93 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL18774788 0.93 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A
SCHEMBL534947 0.93 TP53 (0.73) TP53TSHRPLA2G4BRARBPLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080114-A Composition containing long-chain alkane for polypeptide synthesis and preparation method of polypeptide 2026-05-26 CN disclosed
EP-4673424-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS Regeneron Pharmaceuticals, Inc. (US) 2026-01-07 EP disclosed
WO-2024182268-A1 LIQUID PHASE PEPTIDE SUPPORT SYNTHESIS OF PEPTIDES AND PEPTIDOMIMETICS REGENERON PHARMACEUTICALS, INC. (US) 2024-09-06 WO disclosed
CN-111971293-B Peptide synthesis method JITSUBO株式会社 2024-07-30 CN disclosed
CN-117843715-A Liquid phase synthesis method of melanoputan-II 浙江工业大学 2024-04-09 CN disclosed
CN-117843761-A Method for preparing melanocortin analogue cyclic peptide drug based on hydrophobic label carrier 浙江工业大学 2024-04-09 CN disclosed
EP-2711370-B1 METHOD FOR PRODUCING OLIGONUCLEOTIDES AJINOMOTO KK (JP) 2018-01-03 EP disclosed
US-9670121-B2 Diphenylmethane compound AJINOMOTO CO., INC. (JP) 2017-06-06 US disclosed
US-20160060198-A1 DIPHENYLMETHANE COMPOUND AJINOMOTO CO., INC. (JP) 2016-03-03 US disclosed
US-9169187-B2 Method of making peptides using diphenylmethane compound AJINOMOTO CO., INC. (JP) 2015-10-27 US disclosed
US-9029528-B2 Solution-based method of making oligonucleotides via phosphoramidite coupling AJINOMOTO CO., INC. (JP) 2015-05-12 US disclosed
US-20140213761-A1 DIPHENYLMETHANE COMPOUND AJINOMOTO CO., INC (JP) 2014-07-31 US disclosed
US-8722934-B2 Diphenylmethane compound AJINOMOTO CO., INC. (JP) 2014-05-13 US disclosed
EP-2711370-A1 METHOD FOR PRODUCING OLIGONUCLEOTIDE Ajinomoto Co., Inc. (JP) 2014-03-26 EP disclosed
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2012-11-22 US disclosed
EP-2415745-A1 DIPHENYLMETHANE COMPOUND Ajinomoto Co., Inc. (JP) 2012-02-08 EP disclosed
US-20100249374-A1 DIPHENYLMETHANE COMPOUND AJINOMOTO CO., INC. (JP) 2010-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249374-A1 DIPHENYLMETHANE COMPOUND CCKAR, DNPEP, QPCTL TP53 1289/4885TSHR 2188/4885PLA2G4B 4673/4885
US-20140213761-A1 DIPHENYLMETHANE COMPOUND CCKAR, VIP, CCKBR TP53 2202/4885TSHR 1541/4885PLA2G4B 4856/4885
US-20160060198-A1 DIPHENYLMETHANE COMPOUND CCKAR, VIP, CCKBR TP53 2202/4885TSHR 1541/4885PLA2G4B 4856/4885
US-20120296074-A1 PRODUCTION METHOD OF OLIGONUCLEOTIDE RNGTT, POLM, RNMT TP53 1957/4885TSHR 1572/4885PLA2G4B 3298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.