Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5338261 | 1.00 | BRD4 (0.40) | BRD4CREBBPEZH2MAOAMAOB | |
| SCHEMBL5346418 | 0.90 | GRM2 (0.35) | BRD4CREBBPEZH2MAOAMAOB | |
| SCHEMBL5346415 | 0.90 | GRM2 (0.35) | BRD4CREBBPEZH2MAOAMAOB | |
| SCHEMBL5352483 | 0.89 | MAOA (0.45) | BRD4CREBBPEZH2MAOAMAOB | |
| SCHEMBL5352491 | 0.89 | MAOA (0.45) | BRD4CREBBPEZH2MAOAMAOB | |
| SCHEMBL5351344 | 0.88 | BRD4 (0.40) | BRD4CREBBPEZH2MAOAMAOB | |
| SCHEMBL5351336 | 0.88 | BRD4 (0.40) | BRD4CREBBPEZH2MAOAMAOB | |
| Ammonia Solution, Strong SCHEMBL5342207 | 0.88 | MAOA (0.44) | BRD4CREBBPEZH2MAOAMAOB | |
| SCHEMBL5355190 | 0.86 | PDE1C (0.42) | BRD4CREBBPMAOAMAOBPTGER3 | |
| SCHEMBL5355186 | 0.86 | PDE1C (0.42) | BRD4CREBBPMAOAMAOBPTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |