Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1C | Q14123 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355186 | 1.00 | PDE1C (0.42) | PDE1CCYP11B2BRD4CREBBPPTGER3 | |
| SCHEMBL5341457 | 0.89 | PDE1C (0.35) | PDE1CCYP11B2BRD4CREBBPPTGER3 | |
| SCHEMBL5337231 | 0.88 | MAOA (0.47) | PDE1CCYP11B2BRD4CREBBPPTGER3 | |
| SCHEMBL5337225 | 0.88 | MAOA (0.47) | PDE1CCYP11B2BRD4CREBBPPTGER3 | |
| SCHEMBL5345629 | 0.87 | CYP11B2 (0.39) | PDE1CCYP11B2BRD4CREBBPPTGER3 | |
| SCHEMBL5345634 | 0.87 | CYP11B2 (0.39) | PDE1CCYP11B2BRD4CREBBPPTGER3 | |
| SCHEMBL5346074 | 0.86 | GRM2 (0.37) | PTGER3MAOAMAOBGRM2 | |
| SCHEMBL5338264 | 0.86 | BRD4 (0.40) | BRD4CREBBPPTGER3MAOAMAOB | |
| SCHEMBL5346078 | 0.86 | GRM2 (0.37) | PTGER3MAOAMAOBGRM2 | |
| SCHEMBL5338261 | 0.86 | BRD4 (0.40) | BRD4CREBBPPTGER3MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |