Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.60 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 3/20 | 0.51 |
| ▸ | FAAH | O00519 | 6/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304869 | 1.00 | LTA4H (0.60) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL18302086 | 1.00 | LTA4H (0.60) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL6705352 | 0.94 | LTA4H (0.54) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL18302066 | 0.87 | NR5A1 (0.57) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL17241411 | 0.87 | LTA4H (0.64) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL17247317 | 0.87 | LTA4H (0.64) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL17241274 | 0.87 | LTA4H (0.64) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL13940046 | 0.85 | SLC2A1 (0.54) | LTA4HTP53TSHRMEN1KMT2A | |
| SCHEMBL17241354 | 0.85 | LTA4H (0.66) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL9304906 | 0.84 | LTA4H (0.60) | LTA4HNR5A1TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670121-B2 | Diphenylmethane compound | AJINOMOTO CO., INC. (JP) | 2017-06-06 | — | — | US | disclosed |
| US-20160060198-A1 | DIPHENYLMETHANE COMPOUND | AJINOMOTO CO., INC. (JP) | 2016-03-03 | — | — | US | disclosed |
| US-9169187-B2 | Method of making peptides using diphenylmethane compound | AJINOMOTO CO., INC. (JP) | 2015-10-27 | — | — | US | disclosed |
| US-20140213761-A1 | DIPHENYLMETHANE COMPOUND | AJINOMOTO CO., INC (JP) | 2014-07-31 | — | — | US | disclosed |
| US-8722934-B2 | Diphenylmethane compound | AJINOMOTO CO., INC. (JP) | 2014-05-13 | — | — | US | disclosed |
| EP-2415745-A1 | DIPHENYLMETHANE COMPOUND | Ajinomoto Co., Inc. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20100249374-A1 | DIPHENYLMETHANE COMPOUND | AJINOMOTO CO., INC. (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249374-A1 | DIPHENYLMETHANE COMPOUND | CCKAR, DNPEP, QPCTL | LTA4H 763/4885NR5A1 2883/4885TP53 1289/4885 |
| US-20140213761-A1 | DIPHENYLMETHANE COMPOUND | CCKAR, VIP, CCKBR | LTA4H 754/4885NR5A1 3226/4885TP53 2202/4885 |
| US-20160060198-A1 | DIPHENYLMETHANE COMPOUND | CCKAR, VIP, CCKBR | LTA4H 754/4885NR5A1 3226/4885TP53 2202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.