Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.60 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18302044 | 1.00 | LTA4H (0.60) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL318324 | 0.88 | PLA2G2A (0.49) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL17241411 | 0.87 | LTA4H (0.64) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL17247317 | 0.87 | LTA4H (0.64) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL17241274 | 0.87 | LTA4H (0.64) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL17241354 | 0.85 | LTA4H (0.66) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL18302086 | 0.84 | LTA4H (0.60) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL9304869 | 0.84 | LTA4H (0.60) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL533827 | 0.84 | LTA4H (0.60) | LTA4HNR5A1TP53TSHRPLA2G4B | |
| SCHEMBL2436449 | 0.84 | LTA4H (0.60) | LTA4HNR5A1TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5319079-A | Reacting the 5'-hydroxyl group of a nucleoside-terminated supported oligonucleotide with a trityl or pixyl halide using an anhydrous solvent, a electronegative reagent and a trialkylamine | BECKMAN INSTRUMENTS, INC. (US) | 1994-06-07 | — | — | US | disclosed |