Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 4/20 | 0.59 |
| ▸ | AKT2 | P31751 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342475 | 0.93 | AKT1 (0.59) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5343352 | 0.92 | AKT1 (0.49) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5344445 | 0.89 | AKT1 (0.66) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5317129 | 0.85 | AKT1 (0.48) | AKT1AKT2KDM4EKMT2A | |
| SCHEMBL5458454 | 0.85 | TP53 (0.44) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5336859 | 0.81 | CNR1 (0.46) | AKT1AKT2ALDH1A1HPGD | |
| SCHEMBL5341752 | 0.81 | AKT1 (0.53) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5338301 | 0.77 | AKT1 (0.48) | AKT1AKT2KDM4E | |
| SCHEMBL5334428 | 0.76 | TSPO (0.48) | AKT1AKT2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5343483 | 0.75 | CYP1A2 (0.59) | AKT1AKT2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |