Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 3/20 | 0.43 |
| ▸ | AKT2 | P31751 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5343214 | 0.95 | TDP1 (0.47) | TDP1NR3C1PGRAKT1AKT2 | |
| SCHEMBL5324596 | 0.93 | TDP1 (0.46) | TDP1NR3C1PGRAKT1AKT2 | |
| SCHEMBL5350061 | 0.90 | TDP1 (0.39) | TDP1NR3C1PGRAKT1AKT2 | |
| SCHEMBL5344952 | 0.90 | TDP1 (0.45) | TDP1NR3C1PGRAKT1AKT2 | |
| SCHEMBL5344560 | 0.89 | MAPK14 (0.42) | TDP1NR3C1PGRAKT1AKT2 | |
| SCHEMBL5354199 | 0.89 | NR1H4 (0.44) | TDP1NR3C1PGRAKT1AKT2 | |
| SCHEMBL5338540 | 0.85 | AKT1 (0.46) | TDP1NR3C1PGRAKT1AKT2 | |
| Hydrochloric Acid SCHEMBL5344599 | 0.84 | AKT1 (0.45) | TDP1NR3C1PGRAKT1AKT2 | |
| SCHEMBL5342580 | 0.83 | TDP1 (0.47) | TDP1NR3C1PGRMAOBGRIN1 | |
| SCHEMBL5354165 | 0.82 | AKT1 (0.44) | TDP1AKT1AKT2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |