SCHEMBL5338575

SCHEMBL5338575

C=CCc1cc(-c2ccc(N)c(CC=C)c2)ccc1N

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 8/20 0.59
GABRB2 P47870 8/20 0.59
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
ALOX5 P09917 4/20 0.42
CNR2 P34972 4/20 0.42
POLB P06746 3/20 0.42
MAPT P10636 2/20 0.42
GAA P10253 1/20 0.42
GABRB1 P18505 1/20 0.42
RXRA P19793 1/20 0.42
CNR1 P21554 1/20 0.42
GABRA5 P31644 1/20 0.42
GABRA3 P34903 1/20 0.42
GABRA2 P47869 1/20 0.42
ACE2 Q9BYF1 1/20 0.42
SIRT3 Q9NTG7 1/20 0.42
AKR1B1 P15121 1/20 0.41
CYP3A4 P08684 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8675958 0.92 GABRA1 (0.52) GABRA1GABRB2MEN1KMT2ATDP1
SCHEMBL31290769 0.84 GABRA1 (0.41) GABRA1GABRB2MEN1KMT2ATDP1
SCHEMBL454406 0.84 GABRA1 (0.41) GABRA1GABRB2MEN1KMT2ATDP1
Hydrochloric Acid SCHEMBL6307100 0.83 GABRA1 (0.39) GABRA1GABRB2MEN1KMT2ATDP1
SCHEMBL13978640 0.82 GABRA1 (0.59) GABRA1GABRB2MEN1KMT2AALOX5
SCHEMBL1768780 0.81 XDH (0.48) GABRA1GABRB2MEN1KMT2AALOX5
SCHEMBL8231002 0.80 KCNH2 (0.58)
SCHEMBL13837718 0.79 GABRA1 (0.65) GABRA1GABRB2MEN1KMT2AALOX5
SCHEMBL1269438 0.79 ALDH1A1 (0.45) GABRA1GABRB2POLBALDH1A1IMPDH2
SCHEMBL21587343 0.79 GABRA1 (0.37) GABRA1GABRB2POLBMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105367794-B Soluble thermoplastic polyimide composition and laminate made therefrom 台虹科技股份有限公司 2018-01-26 CN claimed
CN-105015099-A Polyimide/metal composite laminated plate and preparation method thereof TAIFLEX SCIENT CO LTD 2015-11-04 CN claimed
CN-105015099-A Polyimide/metal composite laminated plate and preparation method thereof TAIFLEX SCIENT CO LTD 2015-11-04 CN disclosed
US-20070224691-A1 Composition for measuring concentration of residual chlorine MIURA CO., LTD. 2007-09-27 US disclosed
EP-1837653-A1 Composition for measuring concentration of residual chlorine MIURA CO., LTD. (JP) 2007-09-26 EP disclosed
EP-1095931-B1 Benzidine derivatives and electrophotosensitive material using the same KYOCERA MITA CORP (JP) 2003-02-05 EP disclosed