Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336795 | 0.84 | KDM4E (0.52) | ADORA1ADORA2AKDM4EMAPTCYP1A2 | |
| SCHEMBL27241714 | 0.77 | MAPT (0.51) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11165586 | 0.75 | PGK1 (0.46) | ADORA1ADORA2AKDM4ETDP1L3MBTL1 | |
| SCHEMBL24154751 | 0.74 | KMT2A (0.56) | KDM4EMAPTLMNATDP1L3MBTL1 | |
| SCHEMBL30319960 | 0.74 | KMT2A (0.56) | KDM4EMAPTLMNATDP1L3MBTL1 | |
| SCHEMBL11162556 | 0.73 | PGK1 (0.53) | ADORA1ADORA2APGK1 | |
| SCHEMBL7219112 | 0.73 | ADORA1 (0.53) | ADORA1ADORA2AKDM4EMAPTCYP1A2 | |
| SCHEMBL1904903 | 0.71 | CYP1A2 (0.53) | KDM4EMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5329336 | 0.71 | ADORA1 (0.56) | ADORA1ADORA2AKDM4EMAPTCYP1A2 | |
| SCHEMBL19805092 | 0.71 | MEN1 (0.50) | ADORA1ADORA2AKDM4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029062-A2 | NOVEL PYRIDINE DERIVATIVES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |