SCHEMBL533910

SCHEMBL533910

CC(C)c1ccc(-c2cc[c]cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.42
KIF11 P52732 1/20 0.42
PTPN5 P54829 1/20 0.40
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
NOTUM Q6P988 2/20 0.39
TP53 P04637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TYR P14679 2/20 0.39
ERBB2 P04626 1/20 0.39
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 2/20 0.38
ERN1 O75460 1/20 0.38
FFAR1 O14842 1/20 0.37
HTT P42858 1/20 0.37
IDO1 P14902 2/20 0.35
MAPT P10636 2/20 0.35
PAX8 Q06710 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11032013 0.85 MAPT (0.45) NISCHPTPN5RAB9ANPC1NOTUM
SCHEMBL21459 0.84
SCHEMBL197335 0.84 KIF11 (0.52) NISCHKIF11PTPN5RAB9ANPC1
SCHEMBL27374847 0.81 TYR (0.39) NISCHRAB9ANPC1NOTUMTP53
SCHEMBL28232445 0.81 TYR (0.39) NISCHRAB9ANPC1NOTUMTP53
SCHEMBL27717161 0.81 TYR (0.39) NISCHRAB9ANPC1NOTUMTP53
SCHEMBL28403145 0.81 RXRA (0.34) LMNAERN1
SCHEMBL11046872 0.80 TYR (0.39) NISCHTYRERBB2KDM4EHPGD
SCHEMBL27871094 0.79 TYR (0.37) NISCHTYRKDM4EHPGDLMNA
SCHEMBL27575184 0.79 TYR (0.37) NISCHTYRKDM4EHPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926175-A Halogen-free polyphosphate flame retardant with high polymerization degree and preparation method thereof 缔久高科技材料(南通)有限公司 2023-04-07 CN claimed
EP-1581341-A1 TRIMERISATION OF OLEFINS Sasol Technology (Pty) Ltd (ZA) 2005-10-05 EP claimed
WO-2004056477-A1 TRIMERISATION OF OLEFINS SASOL TECHNOLOGY (PTY) LIMITED (ZA) 2004-07-08 WO claimed
US-5159074-A AMINOMETHANEPHOSPHONIC ACID ARYL ESTERS, A PROCESS FOR THEIR PRODUCTION AND THEIR USE BAYER AKTIENGESELLSCHAFT (DE) 1992-10-27 US claimed
EP-0248404-B1 ETHYLENE COPOLYMERS WITH ENHANCED FIRE RESISTANT PROPERTIES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-04 EP claimed
US-4849135-A ALUMINA, CALCIUM CARBONATE, CALCIUM-MAGNESIUM CARBONATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-18 US claimed
US-4532085-A Extracting esters from distillation residues with hydrocarbon solvent STAUFFER CHEMICAL COMPANY (US) 1985-07-30 US claimed
US-3931367-A Color improvement of phosphate esters STAUFFER CHEMICAL COMPANY (US) 1976-01-06 US claimed
CN-117447408-A N- (2-organic seleno) acrolein quinazolinone and preparation method thereof 江西师范大学 2024-01-26 CN disclosed
EP-4291592-A1 FLAME LAMINATION ADDITIVE FOR POLYURETHANE FOAM ICL-IP America Inc. (US) 2023-12-20 EP disclosed
CN-115926175-A Halogen-free polyphosphate flame retardant with high polymerization degree and preparation method thereof 缔久高科技材料(南通)有限公司 2023-04-07 CN disclosed
WO-2022173532-A1 FLAME LAMINATION ADDITIVE FOR POLYURETHANE FOAM ICL-IP AMERICA INC. (US) 2022-08-18 WO disclosed
EP-3606971-B1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL IP AMERICA INC (US) 2022-01-12 EP disclosed
US-20200181359-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL IP AMERICA INC (US) 2020-06-11 US disclosed
US-4849135-A ALUMINA, CALCIUM CARBONATE, CALCIUM-MAGNESIUM CARBONATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-18 US disclosed
EP-0248404-A2 Ethylene copolymers with enhanced fire resistant properties E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-09 EP disclosed
EP-0005053-B1 FLAME-RETARDANT ORGANIC PHOSPHATES, THEIR PRODUCTION, AND COMPOSITIONS CONTAINING THEM FMC Corporation (US) 1983-05-25 EP disclosed
US-4246169-A Flammable plastics containing a flame retardant amount of polyarylphosphates and the polyarylphosphates FMC CORPORATION (US) 1981-01-20 US disclosed
US-4212832-A REACTING PHOSPHONIC OR PHOSPHORIC ACID ARYL ESTER WITH FORMALDEHYDE AND SULFURIC ACID; FLAME-PROOFING AGENT BAYER AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
EP-0005053-A2 Flame-retardant organic phosphates, their production, and compositions containing them FMC Corporation (US) 1979-10-31 EP disclosed