Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533910 | 0.81 | NISCH (0.42) | ERN1LMNA | |
| SCHEMBL533468 | 0.81 | RXRA (0.54) | RXRARXRBRXRGCA1CA2 | |
| SCHEMBL3691460 | 0.80 | CA1 (0.41) | RXRARXRBRXRGLMNAGABRA1 | |
| SCHEMBL1368891 | 0.77 | ROCK2 (0.40) | GABRA1GABRB2CA1CA2 | |
| SCHEMBL5352792 | 0.76 | RXRA (0.48) | RXRARXRBRXRG | |
| SCHEMBL21459 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL27170336 | 0.74 | RXRA (0.47) | RXRARXRBRXRG | |
| SCHEMBL28893537 | 0.73 | ESR1 (0.56) | RXRARXRBRXRG | |
| SCHEMBL18999637 | 0.73 | MAPT (0.50) | LMNA | |
| SCHEMBL24017151 | 0.72 | KIF11 (0.47) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111057114-A | N-heterocyclic carbene, precursor imidazole salt and transition metal complex thereof, and preparation method and application thereof | 东莞市均成高新材料有限公司 | 2020-04-24 | — | — | CN | claimed |
| CN-111057114-A | N-heterocyclic carbene, precursor imidazole salt and transition metal complex thereof, and preparation method and application thereof | 东莞市均成高新材料有限公司 | 2020-04-24 | — | — | CN | disclosed |