Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 3/20 | 0.51 |
| ▸ | ALDH1A2 | O94788 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333968 | 0.82 | DHODH (0.79) | ALDH1A1NPC1RAB9AKDM4EPKM | |
| SCHEMBL5344215 | 0.77 | DHODH (0.56) | ALDH1A1NPC1RAB9AKDM4EPKM | |
| SCHEMBL5338077 | 0.76 | HTR4 (0.52) | ALDH1A1NPC1RAB9AKDM4EPKM | |
| SCHEMBL5335420 | 0.75 | NR4A2 (0.57) | ALDH1A1NPC1RAB9AKDM4EPKM | |
| SCHEMBL5335058 | 0.74 | DHODH (0.65) | ALDH1A1NPC1RAB9AKDM4EPKM | |
| SCHEMBL28851904 | 0.73 | RAB9A (1.00) | ALDH1A1NPC1RAB9AKDM4EPKM | |
| SCHEMBL18038115 | 0.73 | DHODH (0.50) | ALDH1A1NPC1RAB9AKDM4EPKM | |
| SCHEMBL18038320 | 0.72 | DHODH (0.59) | ALDH1A1NPC1RAB9AKDM4EPKM | |
| SCHEMBL5340752 | 0.72 | CNR1 (0.53) | CNR1 | |
| SCHEMBL12753158 | 0.72 | DHODH (0.69) | ALDH1A1NPC1RAB9AKDM4EDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |