Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.47 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333968 | 0.81 | DHODH (0.79) | DHODHMAPTALDH1A2ALDH1A3NPC1 | |
| SCHEMBL5338077 | 0.78 | HTR4 (0.52) | DHODHALDH1A2ALDH1A3NPC1RAB9A | |
| SCHEMBL5339242 | 0.77 | ALDH1A1 (0.56) | DHODHLMNAMAPTALDH1A2ALDH1A3 | |
| SCHEMBL5335058 | 0.77 | DHODH (0.65) | DHODHMAPTALDH1A2ALDH1A3NPC1 | |
| SCHEMBL8866544 | 0.74 | DHODH (0.52) | DHODHMAPTALDH1A2ALDH1A3NPC1 | |
| SCHEMBL8865976 | 0.73 | DHODH (0.51) | DHODHALDH1A2ALDH1A3NPC1RAB9A | |
| SCHEMBL5318652 | 0.73 | DHODH (0.59) | DHODHMAPTALDH1A2ALDH1A3NPC1 | |
| SCHEMBL10211959 | 0.73 | DHODH (1.00) | DHODHALDH1A2ALDH1A3NPC1RAB9A | |
| SCHEMBL1481133 | 0.73 | DHODH (0.94) | DHODHALDH1A2ALDH1A3NPC1RAB9A | |
| SCHEMBL12753158 | 0.73 | DHODH (0.69) | DHODHLMNAMAPTALDH1A2ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |