Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | LIPE | Q05469 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5502096 | 0.83 | BRD4 (0.39) | BRD4LMNALIPEACACBACACA | |
| SCHEMBL5343866 | 0.82 | GPR35 (0.48) | BRD4LMNALIPEACACBACACA | |
| SCHEMBL5270466 | 0.80 | GPR35 (0.48) | BRD4LMNALIPEACACBACACA | |
| SCHEMBL5518519 | 0.80 | ACACB (0.37) | BRD4LMNALIPEACACBACACA | |
| SCHEMBL5269374 | 0.79 | FFAR4 (0.36) | SCN9A | |
| SCHEMBL5267329 | 0.79 | MCHR1 (0.35) | BRD4KMT2AACACBL3MBTL1SCN9A | |
| SCHEMBL5266914 | 0.79 | MAPT (0.41) | KMT2ARAB9AMEN1POLB | |
| SCHEMBL5269571 | 0.79 | PTGER4 (0.39) | ACACB | |
| SCHEMBL5273163 | 0.79 | PRKAB2 (0.36) | SCN9A | |
| SCHEMBL5506161 | 0.79 | BRD4 (0.38) | BRD4LMNALIPEKMT2AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |