Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5272120 | 0.92 | MCHR1 (0.34) | MCHR1PTPN5PTGESCYP1A2MEN1 | |
| SCHEMBL5571402 | 0.89 | KDM4E (0.43) | MCHR1PTGESCYP1A2MEN1KMT2A | |
| SCHEMBL5338178 | 0.86 | PTGES (0.33) | MCHR1PTPN5PTGESMEN1KMT2A | |
| SCHEMBL5573963 | 0.85 | CYP1A2 (0.34) | MCHR1PTPN5PTGESCYP1A2MEN1 | |
| SCHEMBL5570207 | 0.85 | GPR35 (0.36) | MCHR1PTPN5CYP1A2CYP3A4CYP3A5 | |
| SCHEMBL5573431 | 0.85 | MCHR1 (0.37) | MCHR1PTPN5CYP1A2CYP3A4CYP3A5 | |
| SCHEMBL5574807 | 0.85 | CYP1A2 (0.34) | MCHR1PTPN5PTGESCYP1A2MEN1 | |
| SCHEMBL5350625 | 0.85 | CYP1A2 (0.34) | MCHR1PTPN5PTGESCYP1A2MEN1 | |
| SCHEMBL5509633 | 0.82 | DGAT1 (0.35) | MCHR1PTPN5CYP1A2PPARDDGAT1 | |
| SCHEMBL5574783 | 0.82 | KDM4E (0.44) | MCHR1CYP1A2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838669-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006077365-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |