Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3791696 | 1.00 | ESR1 (0.59) | ESR1ESR2ALOX5CA1CA2 | |
| SCHEMBL27858243 | 0.98 | ESR1 (0.57) | ESR1ESR2ALOX5CA1CA2 | |
| SCHEMBL25205531 | 0.93 | ESR1 (0.52) | ESR1ESR2ALOX5CA1CA2 | |
| SCHEMBL1368974 | 0.93 | ESR1 (0.52) | ESR1ESR2ALOX5CA1CA2 | |
| SCHEMBL2453734 | 0.92 | ESR1 (0.52) | ESR1ESR2ALOX5CA1CA2 | |
| SCHEMBL8589113 | 0.91 | ESR1 (0.57) | ESR1ESR2ALOX5CA1CA2 | |
| SCHEMBL8591440 | 0.89 | ESR1 (0.59) | ESR1ESR2ALOX5CA1CA2 | |
| SCHEMBL31039575 | 0.85 | ESR1 (0.76) | ESR1ESR2ALOX5CA1CA2 | |
| SCHEMBL18260181 | 0.85 | ESR1 (0.76) | ESR1ESR2ALOX5CA1CA2 | |
| SCHEMBL23673997 | 0.85 | ALDH1A1 (0.53) | ESR1ESR2ALOX5CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-111094223-B | binaphthyl compounds | 罗伊特化学仪器制造公司 | 2023-10-27 | — | — | CN | claimed |
| US-20230337532-A1 | TRIAZINE COMPOUND, MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, ELECTRON TRANSPORT MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, AND ORGANIC LIGHT EMITTING DIODE | TOSOH CORPORATION (JP) | 2023-10-19 | — | — | US | claimed |
| CN-110041174-B | EBINOL axis chiral compound and synthetic method and application thereof | 南方科技大学 | 2022-04-12 | — | — | CN | claimed |
| CN-109535018-B | Method for synthesizing binaphthol amine by chiral phosphate catalysis | 南方科技大学 | 2021-07-27 | — | — | CN | claimed |
| CN-112912372-A | Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element | 东曹株式会社 | 2021-06-04 | — | — | CN | claimed |
| CN-109942581-B | Indoline [3,2-a ] carbazole and pyridine derivative, and preparation method, application and device thereof | 武汉尚赛光电科技有限公司 | 2020-09-04 | — | — | CN | claimed |
| CN-111094223-A | Binaphthyl compounds | 罗伊特化学仪器制造公司 | 2020-05-01 | — | — | CN | claimed |
| WO-2020085319-A1 | CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 | 2020-04-30 | — | — | WO | claimed |
| US-10586933-B2 | Electroactive metal complexes | LG CHEM, LTD. (KR) | 2020-03-10 | — | — | US | claimed |
| WO-1998038156-A1 | AMINE COMPOUNDS, THEIR PRODUCTION AND USE AS AMYLOID-BETA PRODUCTION INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-03 | — | — | WO | claimed |
| EP-0810864-A4 | 2,6-DIARYL PYRIDAZINONES WITH IMMUNOSUPPRESSANT ACTIVITY | MERCK & CO INC (US) | 1998-03-04 | — | — | EP | claimed |
| EP-0821665-A1 | CYCLOBUTANE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHASE AND PROTEIN FARNESYLTRANSFERASE | Abbott Laboratories (US) | 1998-02-04 | — | — | EP | claimed |
| EP-0810864-A1 | 2,6-DIARYL PYRIDAZINONES WITH IMMUNOSUPPRESSANT ACTIVITY | Merck & Co., Inc. (US) | 1997-12-10 | — | — | EP | claimed |
| US-5670504-A | 2,6-diaryl pyridazinones with immunosuppressant activity | MERCK & CO. INC. (US) | 1997-09-23 | — | — | US | claimed |
| US-5582942-A | BINDER RESIN COMPRISES A COPOLYMER INCLUDING A (METH)ACRYLIC ACID ESTER CONTAINING AN AROMATIC RING AND A VINYL MONOMER HAVING ONE TO THREE ACID FUNCTIONAL GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-12-10 | — | — | US | claimed |
| WO-1996033159-A1 | CYCLOBUTANE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-10-24 | — | — | WO | claimed |
| EP-0199151-B1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-11-07 | — | — | EP | claimed |
| US-4623661-A | HYDROXAMIC ACID DERIVATIVES | ABBOTT LABORATORIES (US) | 1986-11-18 | — | — | US | claimed |
| EP-0199151-A2 | Lipoxygenase inhibiting compounds | ABBOTT LABORATORIES (US) | 1986-10-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10586933-B2 | Electroactive metal complexes | AFF1, AFF4, AFF2 | ESR1 15/4885ESR2 17/4885ALOX5 3456/4885 |
| US-20230337532-A1 | TRIAZINE COMPOUND, MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, ELECTRON TRANSPORT MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, AND ORGANIC LIGHT EMITTING DIODE | ARNT, TPH1, AHR | ESR1 423/4885ESR2 174/4885ALOX5 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.