Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | NCEH1 | Q6PIU2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | PRNP | P04156 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342448 | 0.87 | PTPN1 (0.38) | CNR1CNR2NCEH1TDP1L3MBTL1 | |
| SCHEMBL5335292 | 0.87 | PTPN1 (0.36) | CNR1CNR2NCEH1TDP1L3MBTL1 | |
| SCHEMBL5335301 | 0.85 | CNR1 (0.38) | CNR1CNR2NCEH1TDP1L3MBTL1 | |
| SCHEMBL5341795 | 0.83 | SMN1; SMN2 (0.34) | CNR1CNR2TDP1L3MBTL1ATM | |
| SCHEMBL6579423 | 0.81 | PTPN1 (0.40) | L3MBTL1ATMSMN1; SMN2HPGDNPC1 | |
| SCHEMBL5338631 | 0.76 | PTPN1 (0.46) | CNR1CNR2SMN1; SMN2HPGDPTPN1 | |
| SCHEMBL5343854 | 0.75 | PTPN1 (0.47) | SMN1; SMN2HPGDPTPN1PRNPRXFP1 | |
| SCHEMBL5344423 | 0.75 | PTPN1 (0.48) | CNR1CNR2NCEH1SMN1; SMN2HPGD | |
| SCHEMBL5340347 | 0.73 | F9 (0.41) | CNR1CNR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL5337137 | 0.73 | F9 (0.41) | CNR1CNR2SMN1; SMN2HPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163954-B2 | Substituted naphthyl benzothiophene acids | WYETH (US) | 2007-01-16 | — | — | US | disclosed |
| US-20050070587-A1 | Substituted naphthyl benzothiophene acids | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070587-A1 | Substituted naphthyl benzothiophene acids | TST, GNPAT, NUDT1 | CNR1 4226/4885CNR2 3680/4885NCEH1 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.