SCHEMBL534197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20773300	0.79	CYP3A4 (0.57)	ALDH1A1MAPTKDM4EGAACYP1A2
	SCHEMBL29809738	0.75	ALDH1A1 (0.56)	ALDH1A1MAPTKDM4ECYP1A2HPGD
	SCHEMBL1945874	0.75	ALDH1A1 (0.56)	ALDH1A1MAPTKDM4ECYP1A2HPGD
	SCHEMBL13241274	0.74	MGLL (0.52)	ALDH1A1MAPTKDM4EGAAMEN1
	SCHEMBL1894192	0.73	GAA (0.46)	ALDH1A1MAPTKDM4EGAAHPGD
	SCHEMBL20773129	0.73	ALDH1A1 (0.40)	ALDH1A1MAPTCYP1A2HPGDMEN1
	SCHEMBL20773261	0.73	NPC1 (0.47)	ALDH1A1MAPTKDM4EGAAHPGD
	SCHEMBL9667159	0.72	KDM4E (0.46)	ALDH1A1MAPTKDM4EGAACYP1A2
	SCHEMBL1021417	0.72	KDM4E (0.52)	ALDH1A1MAPTKDM4EGAACYP1A2
	SCHEMBL30332127	0.72	KDM4E (0.52)	ALDH1A1MAPTKDM4EGAACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.