Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14399299 | 0.91 | TDP1 (0.53) | TDP1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL5344554 | 0.91 | TDP1 (0.53) | TDP1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL4530882 | 0.85 | TDP1 (0.70) | TDP1SMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL502025 | 0.84 | TDP1 (0.68) | TDP1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL17396777 | 0.83 | TDP1 (0.73) | TDP1SMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL17396705 | 0.82 | TDP1 (0.71) | TDP1LMNAKMT2AALDH1A1SLC6A3 | |
| SCHEMBL7761107 | 0.81 | TDP1 (0.63) | TDP1SMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL11148968 | 0.81 | LMNA (0.65) | TDP1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL24178227 | 0.79 | LMNA (0.63) | TDP1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7512736 | 0.79 | TDP1 (0.49) | TDP1SMN1; SMN2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276324-B2 | Nitrogen-containing organic compound, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-10-02 | — | — | US | disclosed |
| US-20050106500-A1 | Nitrogen-containing organic compound, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. | 2005-05-19 | — | — | US | disclosed |