Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 4/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.45 |
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15308482 | 0.81 | HSD17B1 (0.59) | ATRMAP4K4FYNPIK3CDPIK3CA | |
| SCHEMBL2681285 | 0.80 | SMN1; SMN2 (0.51) | ATRMAPTALOX5APFEN1 | |
| SCHEMBL29911143 | 0.79 | PIM1 (0.43) | ATRALOX5APFEN1PIM1 | |
| SCHEMBL20839015 | 0.79 | PIM1 (0.43) | ATRALOX5APFEN1PIM1 | |
| SCHEMBL15308478 | 0.79 | ATR (0.57) | ATRMAP4K4KDM4EMAPTFYN | |
| SCHEMBL15308592 | 0.77 | TYRO3 (0.50) | ATRALOX5APFEN1PIK3CDPIK3CA | |
| SCHEMBL3983850 | 0.77 | ATR (0.72) | ATRHPGDSPIK3CDPIK3CAPIK3CG | |
| SCHEMBL15308501 | 0.77 | ATR (0.61) | ATRMAP4K4ALOX5APFEN1FYN | |
| SCHEMBL3460592 | 0.77 | ATR (0.68) | ATRBCHEACHEMAP4K4HPGDS | |
| SCHEMBL15308481 | 0.74 | ALDH1A1 (0.57) | KDM4EMEN1MAPTKMT2AALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |