SCHEMBL2681285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23732500	0.85	ATR (0.50)	SMN1; SMN2NPC1RAB9AATRALOX5AP
	SCHEMBL29519952	0.82	ATR (0.56)	SMN1; SMN2NPC1PDGFRBKDRFLT3
	SCHEMBL12489014	0.82	ATR (0.56)	SMN1; SMN2NPC1PDGFRBKDRFLT3
	SCHEMBL15308482	0.80	HSD17B1 (0.59)	ATRPRKDCADORA1HDAC6
	SCHEMBL5342191	0.80	ATR (0.53)	ATRALOX5APFEN1MAPT
	SCHEMBL23732523	0.79	RAB9A (0.48)	SMN1; SMN2NPC1RAB9AATRALOX5AP
	SCHEMBL32688927	0.78	ATR (0.66)	ATRPRKDCTLR9
	SCHEMBL6701248	0.78	ATR (0.66)	ATRPRKDCTLR9
	SCHEMBL2912954	0.78	SMN1; SMN2 (0.53)	SMN1; SMN2NPC1PDGFRBKDRFLT3
	SCHEMBL12198431	0.78	ATR (0.56)	ATRPRKDCADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.