Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534328 | 1.00 | NPY5R (0.48) | NPY5RCYP24A1LMNAADRA2BADRA2C | |
| SCHEMBL5648204 | 0.79 | CYP1A2 (0.51) | LMNACYP3A4CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL165658 | 0.74 | HTT (0.40) | LMNACYP3A4CYP2D6CYP1A2ALOX15 | |
| SCHEMBL11588617 | 0.74 | ADRA2B (0.61) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL10944523 | 0.74 | CYP24A1 (0.51) | CYP24A1CYP3A4CYP2D6CYP1A2CYP19A1 | |
| SCHEMBL427205 | 0.74 | KDM4E (0.53) | CYP24A1LMNACYP3A4CYP2D6CYP1A2 | |
| SCHEMBL14008051 | 0.73 | NPY5R (0.55) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL7636285 | 0.73 | NPY5R (0.55) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL7636288 | 0.73 | NPY5R (0.55) | NPY5RADRA2BADRA2CSLC6A2HTR2A | |
| SCHEMBL5651399 | 0.71 | ALDH1A1 (0.53) | CYP24A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256229-A1 | COMPOSITIONS OF CHOLINESTERASE INHIBITORS | COLUCID PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | US | claimed |
| EP-2413926-A2 | COMPOSITIONS OF CHOLINESTERASE INHIBITORS | Colucid Pharmaceuticals, Inc. (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115124-A2 | COMPOSITIONS OF CHOLINESTERASE INHIBITORS | COLUCID PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010115124-A2 | COMPOSITIONS OF CHOLINESTERASE INHIBITORS | COLUCID PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | WO | disclosed |
| US-20100256229-A1 | COMPOSITIONS OF CHOLINESTERASE INHIBITORS | COLUCID PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| US-20100256229-A1 | COMPOSITIONS OF CHOLINESTERASE INHIBITORS | COLUCID PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | US | disclosed |
| US-20100256229-A1 | COMPOSITIONS OF CHOLINESTERASE INHIBITORS | COLUCID PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256229-A1 | COMPOSITIONS OF CHOLINESTERASE INHIBITORS | ACHE, BCHE, CES1 | NPY5R 3047/4885CYP24A1 1975/4885LMNA 4281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.