Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 3/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 6/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344232 | 1.00 | NOTUM (0.43) | NOTUMMCHR2MCHR1MAOAMAOB | |
| SCHEMBL5347451 | 0.85 | NOTUM (0.49) | NOTUMMAOAMAOBCACNA1HNPC1 | |
| SCHEMBL5347454 | 0.85 | NOTUM (0.49) | NOTUMMAOAMAOBCACNA1HNPC1 | |
| SCHEMBL5342407 | 0.83 | ACLY (0.45) | NOTUMMCHR2MCHR1MAOAMAOB | |
| SCHEMBL5342410 | 0.83 | ACLY (0.45) | NOTUMMCHR2MCHR1MAOAMAOB | |
| SCHEMBL5353885 | 0.83 | ACLY (0.37) | NOTUMMCHR2MCHR1MAOAMAOB | |
| SCHEMBL5353882 | 0.83 | ACLY (0.37) | NOTUMMCHR2MCHR1MAOAMAOB | |
| SCHEMBL19790567 | 0.73 | NOTUM (0.42) | NOTUMMAOAMAOBSYKCACNA1H | |
| SCHEMBL20594117 | 0.73 | KDM4E (0.54) | MAOAMAOBCACNA1H | |
| SCHEMBL20332043 | 0.73 | NOTUM (0.54) | NOTUMMCHR1MAOAMAOBSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |