Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.36 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353885 | 1.00 | ACLY (0.37) | ACLYKMOHDAC8MCHR2MCHR1 | |
| SCHEMBL5342410 | 0.90 | ACLY (0.45) | ACLYHDAC8MCHR2MCHR1P2RX3 | |
| SCHEMBL5342407 | 0.90 | ACLY (0.45) | ACLYHDAC8MCHR2MCHR1P2RX3 | |
| SCHEMBL5344232 | 0.83 | NOTUM (0.43) | MCHR2MCHR1MAOBNPC1RAB9A | |
| SCHEMBL5344229 | 0.83 | NOTUM (0.43) | MCHR2MCHR1MAOBNPC1RAB9A | |
| SCHEMBL5347454 | 0.82 | NOTUM (0.49) | MAOBNPC1RAB9ANOTUMMAPT | |
| SCHEMBL5347451 | 0.82 | NOTUM (0.49) | MAOBNPC1RAB9ANOTUMMAPT | |
| SCHEMBL5999445 | 0.70 | BRD4 (0.39) | P2RX3GAA | |
| SCHEMBL5999454 | 0.70 | BRD4 (0.39) | P2RX3GAA | |
| SCHEMBL20665050 | 0.69 | KMO (0.53) | ACLYKMOHDAC8HCAR3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |