Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347451 | 1.00 | NOTUM (0.49) | NOTUMTRPM5NPC1ALDH1A1MAPT | |
| SCHEMBL5342410 | 0.85 | ACLY (0.45) | NOTUMNPC1RAB9AMAOBMAOA | |
| SCHEMBL5344229 | 0.85 | NOTUM (0.43) | NOTUMNPC1RAB9AMAOBMAOA | |
| SCHEMBL5344232 | 0.85 | NOTUM (0.43) | NOTUMNPC1RAB9AMAOBMAOA | |
| SCHEMBL5342407 | 0.85 | ACLY (0.45) | NOTUMNPC1RAB9AMAOBMAOA | |
| SCHEMBL5353882 | 0.82 | ACLY (0.37) | NOTUMNPC1MAPTRAB9AMAOB | |
| SCHEMBL5353885 | 0.82 | ACLY (0.37) | NOTUMNPC1MAPTRAB9AMAOB | |
| SCHEMBL13106705 | 0.78 | TRPM5 (0.56) | NOTUMTRPM5NPC1ALDH1A1MAPT | |
| SCHEMBL13106720 | 0.76 | TRPM5 (0.53) | NOTUMTRPM5NPC1ALDH1A1MAPT | |
| SCHEMBL14035668 | 0.73 | TRPM5 (0.59) | NOTUMTRPM5NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |