Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325683 | 0.89 | AKT1 (0.51) | PTGS2AKT1AKT2 | |
| SCHEMBL5344598 | 0.83 | KMT2A (0.53) | AKT1AKT2NR1I3 | |
| SCHEMBL5342012 | 0.83 | AKT1 (0.44) | PTGS2AKT1AKT2NR1I3PTGS1 | |
| SCHEMBL5349048 | 0.82 | AKT1 (0.48) | PTGS2AKT1AKT2 | |
| SCHEMBL5341386 | 0.80 | AKT1 (0.49) | PTGS2AKT1AKT2 | |
| SCHEMBL5322231 | 0.79 | AKT1 (0.48) | PTGS2AKT1AKT2 | |
| SCHEMBL5342992 | 0.79 | MAPT (0.45) | AKT1AKT2 | |
| SCHEMBL5321406 | 0.79 | AKT1 (0.49) | AKT1AKT2 | |
| SCHEMBL5352678 | 0.79 | AKT1 (0.43) | AKT1AKT2 | |
| SCHEMBL5324372 | 0.78 | AKT1 (0.55) | PTGS2AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |