Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322122 | 0.86 | CNR1 (0.41) | PTGS2CNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5345503 | 0.84 | HSD17B10 (0.47) | NPC1RAB9ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL5318690 | 0.83 | CNR1 (0.58) | CNR1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL5337361 | 0.83 | CNR1 (0.60) | CNR1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL5350264 | 0.83 | CNR1 (0.60) | CNR1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL5323774 | 0.81 | CNR1 (0.43) | PTGS2CNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5355542 | 0.79 | CNR1 (0.59) | CNR1KDM4EALDH1A1TP53HPGD | |
| SCHEMBL5340360 | 0.74 | AKT1 (0.46) | PTGS2NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL5337928 | 0.71 | AKT1 (0.52) | KDM4EDHODHHSD17B10 | |
| SCHEMBL5322344 | 0.71 | AKT1 (0.55) | PTGS2CNR1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |