Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344739 | 0.84 | PTGS2 (0.43) | HSD17B10DPP4DPP8DPP9KDM4E | |
| SCHEMBL5322122 | 0.81 | CNR1 (0.41) | DPP4DPP8DPP9KDM4ESMN1; SMN2 | |
| SCHEMBL5355542 | 0.79 | CNR1 (0.59) | HSD17B10KDM4EALDH1A1HPGDTP53 | |
| SCHEMBL5318690 | 0.79 | CNR1 (0.58) | GABRA2GABRB2DPP4DPP8DPP9 | |
| SCHEMBL5337361 | 0.78 | CNR1 (0.60) | GABRA2GABRB2DPP4DPP8DPP9 | |
| SCHEMBL5350264 | 0.78 | CNR1 (0.60) | GABRA2GABRB2DPP4DPP8DPP9 | |
| SCHEMBL5348576 | 0.77 | AKT1 (0.65) | GABRA2GABRB2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5323774 | 0.76 | CNR1 (0.43) | DPP4DPP8DPP9KDM4EALDH1A1 | |
| SCHEMBL5340340 | 0.76 | SLC2A1 (0.64) | GABRA2GABRB2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5338476 | 0.75 | GABRA2 (0.48) | HSD17B10GABRA2GABRB2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |