Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337361 | 1.00 | CNR1 (0.60) | CNR1DPP4DPP8DPP9PROKR1 | |
| SCHEMBL5318690 | 0.99 | CNR1 (0.58) | CNR1DPP4DPP8DPP9PROKR1 | |
| SCHEMBL5344739 | 0.83 | PTGS2 (0.43) | CNR1DPP4DPP8DPP9POLB | |
| SCHEMBL5322122 | 0.80 | CNR1 (0.41) | CNR1DPP4DPP8DPP9SMN1; SMN2 | |
| SCHEMBL5345503 | 0.78 | HSD17B10 (0.47) | DPP4DPP8DPP9POLBSMN1; SMN2 | |
| SCHEMBL5323774 | 0.77 | CNR1 (0.43) | CNR1DPP4DPP8DPP9SMN1; SMN2 | |
| SCHEMBL4076019 | 0.76 | CNR1 (1.00) | CNR1POLBSMN1; SMN2NPSR1 | |
| SCHEMBL5337716 | 0.74 | CNR1 (0.55) | CNR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5337926 | 0.74 | CNR1 (0.58) | CNR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5322233 | 0.74 | CNR1 (0.58) | CNR1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |