Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16425349 | 0.92 | MAPT (0.41) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL534211 | 0.88 | PDK2 (0.41) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL13962705 | 0.88 | POLB (0.40) | MAPTMEN1KMT2APDK2POLB | |
| SCHEMBL535058 | 0.86 | PDK2 (0.43) | PDK2 | |
| SCHEMBL6577530 | 0.84 | GPR174 (0.47) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL16900315 | 0.83 | GPR174 (0.34) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL13962696 | 0.83 | POLB (0.36) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL3760944 | 0.82 | PDK2 (0.41) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL13962678 | 0.82 | PDK2 (0.33) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4953296 | 0.80 | POLB (0.40) | MAPTMEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415794-A1 | CURABLE COMPOSITION AND CURED PRODUCT THEREOF | Showa Denko K.K. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20120010361-A1 | CURABLE COMPOSITION AND CURED PRODUCT THEREOF | SHOWA DENKO K.K. (JP) | 2012-01-12 | — | — | US | disclosed |