Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.66 |
| ▸ | NQO2 | P16083 | 7/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5343877 | 0.93 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL7017326 | 0.88 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL7016105 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL7970691 | 0.79 | MTNR1A (0.76) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL4266523 | 0.78 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7950130 | 0.78 | MTNR1A (0.86) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL7104353 | 0.78 | MTNR1A (0.86) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL7943633 | 0.76 | MTNR1A (0.68) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7952490 | 0.74 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL7950608 | 0.74 | MTNR1A (0.81) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123529-A1 | Substituted biphenyl compounds | LES LABORATOIRES SERVIER (FR) | 2007-05-31 | — | — | US | disclosed |
| US-7161035-B2 | Substituted biphenyl derivatives, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2007-01-09 | — | — | US | disclosed |
| US-20040014969-A1 | Substituted biphenyl derivatives, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2004-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014969-A1 | Substituted biphenyl derivatives, method for preparing same and pharmaceutical compositions containing same | MTNR1A, MTNR1B, MC2R | MTNR1A 1/4885MTNR1B 2/4885NQO2 406/4885 |
| US-20070123529-A1 | Substituted biphenyl compounds | MTNR1A, MTNR1B, CNR1 | MTNR1A 1/4885MTNR1B 2/4885NQO2 522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.