SCHEMBL5345282

SCHEMBL5345282

CCOC(=O)C1C(C)(C)OC(=O)C1(C)O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
GAA P10253 1/20 0.41
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.37
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PPM1B O75688 1/20 0.35
PTPN1 P18031 1/20 0.35
PPP1CC P36873 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3688695 0.69 LMNA (0.46) LMNAGAAKDM4EALDH1A1TSHR
SCHEMBL4611550 0.67 ALDH1A1 (0.49) LMNAGAAKDM4EALDH1A1TSHR
SCHEMBL900783 0.66 LMNA (0.43) LMNAGAAKDM4EALDH1A1TSHR
SCHEMBL26751140 0.66 LMNA (0.43) LMNAGAAKDM4EALDH1A1TSHR
SCHEMBL11319249 0.66 LMNA (0.40) LMNAGAAALDH1A1ALOX15PPM1B
SCHEMBL12724372 0.65 LMNA (0.42) LMNAGAAKDM4EALDH1A1TSHR
SCHEMBL7770842 0.65 LMNA (0.39) LMNAGAAKDM4EALDH1A1TSHR
SCHEMBL12919612 0.63 ATM (0.46) KDM4EALDH1A1TSHRALOX15KMT2A
SCHEMBL23461809 0.63 ALDH1A1 (0.36) LMNAGAAKDM4EALDH1A1TSHR
SCHEMBL29191657 0.63 ALDH1A1 (0.39) LMNAGAAKDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183423-B1 Process for the preparation of organic compounds with imide catalysts DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-02-27 US disclosed
EP-1055654-A1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH IMIDE CATALYSTS Daicel Chemical Industries, Ltd. (JP) 2000-11-29 EP disclosed