SCHEMBL900783

SCHEMBL900783

CCOC(=O)C1OC1(C)C

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
POLB P06746 1/20 0.41
ALDH1A1 P00352 3/20 0.40
PPM1B O75688 1/20 0.39
PTPN1 P18031 1/20 0.39
PPP1CC P36873 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 1/20 0.38
GAA P10253 2/20 0.37
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967349 0.83 PPM1B (0.42) LMNAPOLBALDH1A1PPM1BPTPN1
SCHEMBL2139493 0.81 LMNA (0.40) LMNAPOLBALDH1A1PPM1BPTPN1
SCHEMBL14967555 0.79 ALDH1A1 (0.47) LMNAPOLBALDH1A1TSHR
SCHEMBL14966710 0.78 SOAT1 (0.39) LMNAPOLBALDH1A1PPM1BPTPN1
SCHEMBL14967620 0.78 NAAA (0.46) LMNAALDH1A1TSHR
SCHEMBL8076664 0.77 LMNA (0.37) LMNAPOLBALDH1A1PPM1BPTPN1
SCHEMBL8076662 0.77 LMNA (0.37) LMNAPOLBALDH1A1PPM1BPTPN1
SCHEMBL14967677 0.77 NAAA (0.48) LMNAALDH1A1TSHR
SCHEMBL13422928 0.76 TSHR (0.44) LMNAALDH1A1PPM1BPTPN1PPP1CC
SCHEMBL2749084 0.76 TSHR (0.44) LMNAALDH1A1PPM1BPTPN1PPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US claimed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP claimed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US claimed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP claimed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO claimed
US-20240383870-A1 HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF ALDEYRA THERAPEUTICS, INC. 2024-11-21 US disclosed
EP-4362930-A1 HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF Aldeyra Therapeutics, Inc. (US) 2024-05-08 EP disclosed
CN-117580569-A Heterocyclic aldehyde capture compounds and uses thereof 奥尔德拉医疗公司 2024-02-20 CN disclosed
WO-2023180189-A1 MPRO TARGETING ANTIVIRAL COMPOUNDS EXSCIENTIA AI LIMITED (GB) 2023-09-28 WO disclosed
WO-2023278816-A1 HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF ALDEYRA THERAPEUTICS, INC. (US) 2023-01-05 WO disclosed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-5387575-A Pyrimidine derivatives, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1995-02-07 US disclosed
US-5178663-A Pyrimidinyloxy or pyrimidinylthio compounds UBE INDUSTRIES, LTD. (JP) 1993-01-12 US disclosed
CN-1067651-A Pyrimidine or triazine derivative, their preparation method and use them as weedicide UBE INDUSTRIES (JP) 1993-01-06 CN disclosed
EP-0517215-A1 Pyrimidine or triazine derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1992-12-09 EP disclosed
EP-0153692-B1 METHOD FOR ISOMERIZATION A GLYCIDATE DERIVATIVE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-07-29 EP disclosed
EP-0481512-A1 3-Alkoxyalkanoic acid derivative, process for preparing the same and herbicide using the same UBE INDUSTRIES, LTD. (JP) 1992-04-22 EP disclosed
US-4621150-A METAL PERHALATE OR SULFONATE OR COMPLEX; GLYCIDATE, 2-HYDROXY-3-BUTENOATE, EPOXIDE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1986-11-04 US disclosed
EP-0153692-A2 Method for isomerization a glycidate derivative SAGAMI CHEMICAL RESEARCH CENTER (JP) 1985-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383870-A1 HETEROCYCLIC ALDEHYDE TRAPPING COMPOUNDS AND USES THEREOF ALDH1A2, ALDH2, SSB LMNA 2267/4885POLB 4081/4885ALDH1A1 4/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.