Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTSV | O60911 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341496 | 0.96 | BCHE (0.34) | CA12CA7CA9CA14CYP2D6 | |
| SCHEMBL14590797 | 0.96 | BCHE (0.34) | CA12CA7CA9CA14CYP2D6 | |
| SCHEMBL5342197 | 0.93 | FFAR1 (0.33) | CYP2D6LMNACTSVCTSLCTSB | |
| SCHEMBL5341659 | 0.92 | SLC18A3 (0.37) | CYP2D6MAPTLMNACTSVCTSL | |
| SCHEMBL14590785 | 0.90 | BCHE (0.39) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL5340543 | 0.90 | CYP3A4 (0.34) | CYP2D6MAPTLMNACTSVCTSL | |
| SCHEMBL5336900 | 0.90 | BCHE (0.35) | CYP2D6LMNACTSVCTSLCTSB | |
| SCHEMBL5345608 | 0.90 | BCHE (0.36) | CTSVCTSLCTSBCTSSCTSK | |
| SCHEMBL5343162 | 0.90 | BCHE (0.32) | CYP2D6LMNACTSVCTSLCTSB | |
| SCHEMBL14590796 | 0.90 | BCHE (0.32) | CYP2D6LMNACTSVCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6624306-B2 | Stabilizer for addition polymer | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-23 | — | — | US | claimed |
| US-20030166939-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | NESVADBA PETER (CH) | 2003-09-04 | — | — | US | claimed |
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-04-03 | — | — | US | claimed |
| US-7160966-B2 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160966-B2 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160966-B2 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2007-01-09 | — | — | US | disclosed |
| US-20050143539-A1 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | NESVADBA PETER (CH) | 2005-06-30 | — | — | US | disclosed |
| US-6624306-B2 | Stabilizer for addition polymer | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-09-23 | — | — | US | disclosed |
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166939-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | CA12 4742/4885CA7 4181/4885CA9 4240/4885 |
| US-20050143539-A1 | 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | CA12 4742/4885CA7 4181/4885CA9 4240/4885 |
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | CA12 4742/4885CA7 4181/4885CA9 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.