Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.35 |
| ▸ | CALML3 | P27482 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345682 | 1.00 | MAOA (0.45) | MAOASYKMAOBMCHR1MCHR2 | |
| SCHEMBL5346074 | 0.89 | GRM2 (0.37) | MAOASYKMAOBMCHR1MCHR2 | |
| SCHEMBL5345174 | 0.89 | GRIN1 (0.35) | MAOASYKMAOBMCHR1MCHR2 | |
| SCHEMBL5346078 | 0.89 | GRM2 (0.37) | MAOASYKMAOBMCHR1MCHR2 | |
| SCHEMBL5345167 | 0.89 | GRIN1 (0.35) | MAOASYKMAOBMCHR1MCHR2 | |
| SCHEMBL5337231 | 0.85 | MAOA (0.47) | MAOAMAOB | |
| SCHEMBL5337225 | 0.85 | MAOA (0.47) | MAOAMAOB | |
| SCHEMBL14437182 | 0.83 | MAOA (0.42) | MAOAMAOBCALML3GRM2KMO | |
| SCHEMBL5352491 | 0.83 | MAOA (0.45) | MAOAMAOBCALML3CACNA1HCHEK1 | |
| SCHEMBL5352483 | 0.83 | MAOA (0.45) | MAOAMAOBCALML3CACNA1HCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | claimed |
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |