Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.36 |
| ▸ | GLRB | P48167 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337225 | 1.00 | MAOA (0.47) | MAOACYP11B2PDE1CBRD4CREBBP | |
| SCHEMBL5355186 | 0.88 | PDE1C (0.42) | MAOACYP11B2PDE1CBRD4CREBBP | |
| SCHEMBL5345629 | 0.88 | CYP11B2 (0.39) | MAOACYP11B2PDE1CBRD4CREBBP | |
| SCHEMBL5355190 | 0.88 | PDE1C (0.42) | MAOACYP11B2PDE1CBRD4CREBBP | |
| SCHEMBL5345634 | 0.88 | CYP11B2 (0.39) | MAOACYP11B2PDE1CBRD4CREBBP | |
| SCHEMBL5345693 | 0.85 | MAOA (0.45) | MAOAMAOB | |
| SCHEMBL5352491 | 0.85 | MAOA (0.45) | MAOABRD4CREBBPPTGER3MAOB | |
| SCHEMBL5345682 | 0.85 | MAOA (0.45) | MAOAMAOB | |
| SCHEMBL5352483 | 0.85 | MAOA (0.45) | MAOABRD4CREBBPPTGER3MAOB | |
| Ammonia Solution, Strong SCHEMBL5342207 | 0.84 | MAOA (0.44) | MAOABRD4CREBBPPTGER3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |