Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336981 | 0.90 | MAPT (0.41) | MAPTKDM4ENPSR1L3MBTL1AKT1 | |
| SCHEMBL5325683 | 0.84 | AKT1 (0.51) | MAPTKDM4EL3MBTL1AKT1AKT2 | |
| SCHEMBL5341386 | 0.82 | AKT1 (0.49) | KDM4EL3MBTL1AKT1AKT2ALDH1A1 | |
| SCHEMBL5349048 | 0.81 | AKT1 (0.48) | MAPTKDM4EAKT1AKT2KMT2A | |
| SCHEMBL5322231 | 0.81 | AKT1 (0.48) | KDM4EAKT1AKT2ALDH1A1GAA | |
| SCHEMBL5324372 | 0.80 | AKT1 (0.55) | MAPTKDM4EL3MBTL1AKT1AKT2 | |
| SCHEMBL5341370 | 0.80 | MAP4K4 (0.52) | AKT1AKT2 | |
| SCHEMBL5345880 | 0.79 | PTGS2 (0.55) | AKT1AKT2 | |
| SCHEMBL5345483 | 0.79 | NR4A2 (0.51) | AKT1AKT2MAPK1RPS6KA3PSD | |
| SCHEMBL5338540 | 0.78 | AKT1 (0.46) | KDM4EAKT1AKT2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | claimed |
| WO-2007096764-A2 | BICYCLIC HETEROARYL DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-08-30 | — | — | WO | disclosed |