Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221769 | 0.77 | ALDH1A1 (0.39) | MEN1GAAKMT2ASLC7A5ALDH1A1 | |
| SCHEMBL5209072 | 0.77 | ALDH1A1 (0.39) | MEN1GAAKMT2ASLC7A5ALDH1A1 | |
| Methylmalonic Acid SCHEMBL28186298 | 0.76 | CYP2D6 (0.38) | MEN1GAAKMT2ACYP2D6CA2 | |
| SCHEMBL181731 | 0.75 | CYP2D6 (0.43) | MEN1GAAKMT2ACYP2D6CA2 | |
| SCHEMBL28314694 | 0.74 | MEN1 (0.41) | MEN1GAAKMT2ACYP2D6CA2 | |
| SCHEMBL241533 | 0.73 | DGAT1 (0.46) | MEN1GAAKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL27572160 | 0.73 | CYP2D6 (0.39) | MEN1GAAKMT2ACYP2D6CA2 | |
| SCHEMBL5346485 | 0.73 | MEN1 (0.35) | MEN1GAAKMT2ASLC7A5CA2 | |
| SCHEMBL38112 | 0.72 | GRIK1 (0.47) | CYP2D6SLC7A5HDAC3HDAC1HDAC2 | |
| SCHEMBL2024581 | 0.72 | GRIK1 (0.47) | CYP2D6SLC7A5HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007096334-A1 | PYRROLOPYRROLONES ACTIVE AS KINASE INHIBITORS | PFIZER ITALIA SRL (IT) | 2007-08-30 | — | — | WO | disclosed |