Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.50 |
| ▸ | PTPRF | P10586 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693987 | 1.00 | PTPN1 (0.50) | PTPN1PTPN2PTPRFKMT2ANPSR1 | |
| SCHEMBL5342278 | 1.00 | PTPN1 (0.50) | PTPN1PTPN2PTPRFKMT2ANPSR1 | |
| SCHEMBL11492699 | 0.77 | CHRM2 (0.50) | CHRNA7CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL31307177 | 0.74 | ALDH1A1 (0.59) | PTPN1PTPN2PTPRFKMT2ANPSR1 | |
| SCHEMBL16428864 | 0.74 | PTPN2 (0.56) | PTPN1PTPN2PTPRFKMT2ANPSR1 | |
| SCHEMBL21374400 | 0.71 | PTPN2 (0.57) | PTPN1PTPN2PTPRFKMT2ANPSR1 | |
| SCHEMBL11937115 | 0.69 | CHRNA7 (0.51) | PTPN1PTPN2PTPRFKMT2ANPSR1 | |
| SCHEMBL14315917 | 0.68 | PTPRF (0.53) | PTPN1PTPN2PTPRFKMT2ANPSR1 | |
| SCHEMBL16311866 | 0.68 | CHRM2 (0.56) | KMT2AMEN1CHRNA7CHRM2CHRM4 | |
| SCHEMBL27964590 | 0.68 | PTPN2 (0.71) | PTPN1PTPN2PTPRFKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279601-B2 | Optically active α-aminooxyketone derivatives and process for production thereof | TOKYO UNIVERSITY OF SCIENCE, CENTER FOR SCIENCE AND TECHNOLOGY EXCHANGE (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060293525-A1 | Optically active alpha-aminooxyketone derivatives and process for production thereof | TOKYO UNIVERSITY OF SCIENCE, CENTER FOR SCIENCE AND TECHNOLOGY EXCHANGE (JP) | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293525-A1 | Optically active alpha-aminooxyketone derivatives and process for production thereof | ALDH7A1, ASPH, KMO | PTPN1 4553/4885PTPN2 4634/4885PTPRF 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.