SCHEMBL5347354

SCHEMBL5347354

CCOC(=O)c1ccc(N)cc1C/C=C/c1ccc(OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.46
PTGER3 P43115 1/20 0.46
PTGER2 P43116 1/20 0.46
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
MAPT P10636 3/20 0.43
HSD17B10 Q99714 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
CASP3 P42574 1/20 0.43
RAB9A P51151 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
LMNA P02545 2/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5347356 1.00 PTGER4 (0.46) PTGER4PTGER3PTGER2KDM4EALDH1A1
SCHEMBL11501050 0.80 LMNA (0.47) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL10082826 0.77 LMNA (0.53) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL11784914 0.77 LMNA (0.56) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL15835741 0.74 LMNA (0.50) ALDH1A1HPGDMAPTHSD17B10MEN1
SCHEMBL14465366 0.73 LMNA (0.51) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL8191128 0.73 LMNA (0.51) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL4551259 0.72 HPGD (0.57) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL6579313 0.71 SMN1; SMN2 (0.43) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL7978838 0.71 ALDH1A1 (0.58) KDM4EALDH1A1HPGDMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7186448-B2 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2007-03-06 US disclosed
US-20060275939-A1 Composition and method for temporarily fixing solids JSR CORPORATION (JP) 2006-12-07 US disclosed
EP-1522567-A1 COMPOSITION AND METHOD FOR TEMPORARILY FIXING SOLID JSR Corporation (JP) 2005-04-13 EP disclosed
US-20040185187-A1 Composition and method for temporarily fixing solid JSR CORPORATION (JP) 2004-09-23 US disclosed