Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784914 | 0.85 | LMNA (0.56) | LMNAMAOACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL10082826 | 0.82 | LMNA (0.53) | LMNAMAOACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL14465366 | 0.81 | LMNA (0.51) | LMNAMAOACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL8191128 | 0.81 | LMNA (0.51) | LMNAMAOACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL8117430 | 0.80 | CYP4F2 (0.48) | LMNAMAOACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL5347354 | 0.80 | PTGER4 (0.46) | LMNACYP3A4ALDH1A1GAAHSD17B10 | |
| SCHEMBL5347356 | 0.80 | PTGER4 (0.46) | LMNACYP3A4ALDH1A1GAAHSD17B10 | |
| SCHEMBL15835741 | 0.79 | LMNA (0.50) | LMNAMAOACYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL11499774 | 0.79 | ALDH1A1 (0.50) | LMNACYP1A2CYP3A4ALDH1A1GAA | |
| SCHEMBL9307300 | 0.78 | LMNA (0.49) | LMNAMAOACYP1A2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187186-A | WEAR, OXIDATION AND CORROSION RESISTANT | MOBIL OIL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |