Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933256 | 0.85 | ATM (0.46) | PARP1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL5566147 | 0.82 | PARP1 (0.59) | PARP1KMT2AALDH1A1PKMERCC5 | |
| SCHEMBL17244256 | 0.80 | PARP1 (0.57) | PARP1KMT2AALDH1A1PKMERCC5 | |
| SCHEMBL10923792 | 0.79 | TPMT (0.52) | PARP1ALDH1A1RAB9ACYP3A4FLT1 | |
| SCHEMBL3693409 | 0.78 | CA12 (0.52) | KMT2APKMHPGDL3MBTL1CYP1A2 | |
| SCHEMBL29661090 | 0.78 | CA12 (0.52) | KMT2APKMHPGDL3MBTL1CYP1A2 | |
| SCHEMBL22187989 | 0.78 | CA12 (0.57) | PARP1KMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL10750765 | 0.77 | PARP1 (0.44) | PARP1KMT2AALDH1A1PKMKDM4E | |
| SCHEMBL10750769 | 0.77 | PARP1 (0.44) | PARP1KMT2AALDH1A1PKMKDM4E | |
| Water SCHEMBL1456948 | 0.77 | PARP1 (0.63) | PARP1ERCC5FEN1KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596885-A | Process for the preparation of phenylglyoxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-24 | — | — | US | claimed |
| US-4456565-A | BY REACTING ANHYDRIDE WITH ANHYDROUS HYDROCYANIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1984-06-26 | — | — | US | claimed |
| US-4302583-A | BY HEATING THE CORRESPONDING DIMERIC ACYL CYANIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-24 | — | — | US | claimed |
| US-4238412-A | CYANATION OF THE ANHYDRIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | claimed |
| EP-3773012-A1 | COMPOSITION FOR USE IN PREVENTION OR REDUCTION OF OXIDATIVE STRESS AND NEURODEGENERATIVE DISEASES | Rasi, Simo (FI) | 2021-02-17 | — | — | EP | disclosed |
| WO-2020212645-A1 | COMPOSITION FOR USE IN PREVENTION OR REDUCTION OF OXIDATIVE STRESS AND NEURODEGENERATIVE DISEASES | RASI SIMO (FI) | 2020-10-22 | — | — | WO | disclosed |
| US-20190050533-A1 | Redox-related context adjustments to a reference bioprocess model used in learning systems and methods based on redox indicators | PTC THERAPEUTICS, INC. | 2019-02-14 | — | — | US | disclosed |
| US-7250278-B2 | α-keto acid reductase, method for producing the same, and method for producing optically active α-hydroxy acids using the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-07-31 | — | — | US | disclosed |
| US-6777224-B2 | FROM PHENYLGLYOXYLIC ACID USING MICROORGANISMS IN CULTURE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| CN-1497046-A | Alpha ketonic acid reductase and its preparation method, and method of preparing optical active alpha hydroxy acid using said reductase | 大赛璐化学工业株式会社 | 2004-05-19 | — | — | CN | disclosed |
| US-20040086993-A1 | Alpha-keto acid reductase, method for producing the same, and method for producing optically active alpha-hydroxy acids using the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1382674-A2 | Alpha-keto acid reductase, method for producing the same, and method for producing optically active alpha-hydroxy acids using the same | Daicel Chemical Industries, Ltd. (JP) | 2004-01-21 | — | — | EP | disclosed |
| US-4302583-A | BY HEATING THE CORRESPONDING DIMERIC ACYL CYANIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-11-24 | — | — | US | disclosed |
| US-4284584-A | REACTING AN ANHYDRIDE WITH AN ALKALI METAL CYANIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| EP-0005484-B1 | PROCESS FOR THE PREPARATION OF ACYL CYANIDES | BAYER AG (DE) | 1980-12-10 | — | — | EP | disclosed |
| US-4238412-A | CYANATION OF THE ANHYDRIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4228082-A | FUNGICIDES OR CHEMICAL INTERMIDIATES FOR 1,2,4-TRIAZINONE HERBICIDES | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-10-14 | — | — | US | disclosed |
| US-4224226-A | FUNGICIDES BY CONDENSING AN ACYL CYANIDE WITH EITHER A TERTIARY ALCOHOL OR AN ALKENE | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-09-23 | — | — | US | disclosed |
| EP-0005484-A1 | Process for the preparation of acyl cyanides | BAYER AG (DE) | 1979-11-28 | — | — | EP | disclosed |
| US-4143068-A | PROCESS FOR THE PREPARATION OF ACYL CYANIDE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040086993-A1 | Alpha-keto acid reductase, method for producing the same, and method for producing optically active alpha-hydroxy acids using the same | DHCR7, HSD17B12, DLD | PARP1 4119/4885KMT2A 673/4885ALDH1A1 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.