Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351271 | 0.86 | — | — | |
| SCHEMBL3330569 | 0.80 | — | — | |
| SCHEMBL22871208 | 0.80 | — | — | |
| SCHEMBL23251393 | 0.80 | — | — | |
| SCHEMBL10351818 | 0.80 | CYP2D6 (0.41) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| SCHEMBL16553312 | 0.80 | CYP2D6 (0.39) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| SCHEMBL27663525 | 0.75 | CYP2D6 (0.43) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| SCHEMBL13961615 | 0.75 | CYP2D6 (0.43) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| SCHEMBL2279513 | 0.75 | CYP2D6 (0.43) | CYP2D6MEN1ALDH1A1LMNATP53 | |
| SCHEMBL27577662 | 0.75 | CYP2D6 (0.43) | CYP2D6MEN1ALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244852-B2 | Process for preparing 2-methylpyrrolidine and specific enantiomers thereof | ABBOTT LABORATORIES (US) | 2007-07-17 | — | — | US | disclosed |
| EP-1601650-A2 | PROCESS FOR PREPARING 2-METHYLPYRROLIDINE AND SPECIFIC ENANTIOMERS THEREOF | Abbott Laboratories (US) | 2005-12-07 | — | — | EP | disclosed |
| US-20040260100-A1 | Process for preparing 2-methylpyrrolidine and specific enantiomers thereof | ABBVIE INC. | 2004-12-23 | — | — | US | disclosed |
| WO-2004076388-A2 | PROCESS FOR PREPARING 2-METHYLPYRROLIDINE AND SPECIFIC ENANTIOMERS THEREOF | ABBOTT LABORATORIES (US) | 2004-09-10 | — | — | WO | disclosed |
| US-20040171845-A1 | Process for preparing 2-methylpyrrolidine and specific enantiomers thereof | ABBOTT LABORATORIES | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171845-A1 | Process for preparing 2-methylpyrrolidine and specific enantiomers thereof | QDPR, PNMT, MTAP | CYP2D6 10/4885MEN1 2026/4885ALDH1A1 1193/4885 |
| US-20040260100-A1 | Process for preparing 2-methylpyrrolidine and specific enantiomers thereof | QDPR, PNMT, MTAP | CYP2D6 10/4885MEN1 2026/4885ALDH1A1 1193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.